Important Drug Alert For Diabetics!

The U.S. Food and Drug Administration (FDA) safety review has recently issued warnings for a commonly used drug for type 2 diabetes. If you are anyone in your family is taking anti-diabetes medications, please read the drug alert carefully.

1 . What Is The Warning?

According to the warning, diabetes medicines containing saxagliptin may increase the risk of heart failure, particularly in patients who already have heart or kidney disease.

2 . What Is Saxagliptin? ( Common brand names: Kombiglyze, Onglyza)

-Saxagliptin belongs to the the class of dipeptidyl peptidase-4 (DPP-4) inhibitor drugs, which are used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

-Saxagliptin acts by inhibiting the enzyme (dipeptidyl peptidase-4 (DPP-4)) which prevents the breakdown of substances called as incretins, ultimately increasing the production of insulin that reduces blood glucose level at fasting and after intake of food.

-Saxagliptin is available as single-ingredient product or in combination with other diabetes medications such as metformin.

3 . What Should The Patients Taking These Medicines Do?

-Patients should not stop taking their medicine without first talking to their doctor.

-Patients who have a pre-existing heart or kidney disease should immediately consult their doctor .

-Patients who do not have any pre existing heart and kidney problems should also seek their doctor’s opinion regarding the use of this medicine.

-Patients should immediately contact their doctor if they develop signs and symptoms of heart failure such as:

-Unusual shortness of breath during daily activities

-Trouble breathing when lying down

-Tiredness, weakness, or fatigue

-Weight gain with swelling in the ankles, feet, legs, or abdomen more  

Gliptins is the only family of drugs which help improve the health of beta cells responsible for production of insulin in the human body. They do have side effects and it is best to discuss this with your doctor.

Three approved gliptins in use in India are Sitagliptin, Vidagliptin and Saxagliptin. These may be prescribed on their own or in combination with metformin etc. in various medicines. Sitagliptin seems to be the 'better one' of the lot but again your doctor is the best judge. more  
Thank you Mr Pijush Kanti Majumdar & Mr RAMACHANDRA HOSURSRIKANTAIAH for liking the post. more  
it is said if u take more Karela or Loki juice that is also bad for
health.....jai to jaye kahan.

On Mon, Oct 3, 2016 at 9:32 AM, RAMACHANDRA HOSURSRIKANTAIAH <> wrote:

> more  
You forget that you are guinea pig for all medicine and if nothing adverse only then American uses
So long as doctors enjoy free trips abroad and hefty gifts from drug manufacture you will get prescription for unwanted tests,prohibited and unsafe drugs. more  
Sir it is india....yesterday i saw Govt estt has given 'phensydil' to a
lady. entroquinal is still in sell. Edhar sab bhagaban bharosey. in the
long run we are all dead.

On Sun, Oct 2, 2016 at 9:00 PM, Pritam Sharma <>

> more  
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