E484K coronavirus variant neutralising antibodies

This is from a school classmate in USA. Basically saying E484K coronavirus variant from Brazil is neutralising Covid antibodies and may evade the vaccine. So localcircles please escalate this to decision makers and ask them to ban flights from South America in addition to UK South Africa.

You know how the world put travel bans against UK travel out of fear of the B117 more contagious variant? Well, now, UK put travel ban from Latin America & Portugal because U.K. thinks Brazil COVID19 variant is worse.

At least two coronavirus variants are currently circulating in Brazil, and at least one has slipped its borders, traveling to Japan. Japanese authorities found one of those variants in four people traveling from Brazil earlier this week...

The variant contains a mutation that has been linked with higher contagiousness, similar to the variant found in UK and another in South Africa. Like the variant found in South Africa, the one exported from Brazil to Japan also carries a mutation that may weaken the efficacy of vaccines

This same mutation has also been identified in the other coronavirus variant recently discovered in Brazil. Experts have cautioned, however, that it would be very difficult for new variants of the coronavirus to evade vaccines entirely.

The Brazil variant Has been renamed to B1128– more specifically B.1.1.28(K417N/E484K/N501Y). There is another one called B.1.1.28(E484K)—both have the problematic E484K mutation that can escape antibodies!

Why are we so worried about this one? Because like the South Africa B1351 variant, the new ones also have the E484K mutation. In a recent study, E484 mutation (inside the SARSCoV2’s spike’s critical receptor binding domain) seemed to escape neutralizing antibodies—bad.

Well, How much escape? the E484K shows a 10x reduction of neutralization (“neutralization” = stopping the virus)
by various antibodies compared to wildtype (common SARSCoV2) in some patients —a rather bad thing. It means the virus with E484K is worrying for “immune escape”. more  

View all 11 comments Below 11 comments
1-2-3. Mask, Hand sanitizing, Social distancing. again 1-2-3. Keep on doing so ling Corona is alive. more  
The dangerous effect of the COVID virus variant has been reduced. Let the countries concentrate on back ground in the evolution of Corona virus. Is it the creation of Chine scientists. more  
If you care about the well being in the whole, stop posting this sort of useless junk. Try posting issues that is going to help the country move to better days after this horrible virus. Thank you very much. more  
Useful message. But, no use to tell present insensitive govt here. Their prime intention is to get more persons infected, hospitalised, hospitals loot them, some 50:50 goes to govt. I am very serious while writing this reply. more  
do you mean to say that the current vaccine will not work for against those two variants? I think the medical/pharma mafia is taking the human beings as real gineapigs. Govt can only agree to what they say and execute. Sorry state of affairs. God can also not help in this situation. more  
Post a Comment

Related Posts

    • Remdesivir Shortage and Distributors Data

      Hello all: I saw this poll by LocalCircles on shortage of Remdesivir. Had this data on all the distributors of Remdesivir across India so thought I’d share in case anyone or their family has ...

      By Sobhita D
    • Failure to handle COVID

      I am reiterating Saritas post on the fact that our Governments and Experts are failing us people with stats from yesterday. Decisive actions are needed. The current approach is a failed one. ...

      By Nalini R Malik
    • B.1.617- Questions we demand answers to

      I am so disappointed in our Indian scientists and experts of genomics. They took forever to figure out what was going on with this big massive wave across India. We had 216,000+ cases reported yest...

      By Sarita Ravichandran
    • Remdesivir Availability

      I was talking to some folks in Pharma Dept Govt of India yday and was told that they received a LocalCircles letter on April 11 which was then taken seriously by officials. Subsequently...

      By Vikram Gupta
    • India Mutant is here

      NIV, Pune data today says Double Mutant B 1.617 (E484Q + L452R) is in 60% samples genome sequenced from Jan-March 2021 in Maharashtra. We need to track mutations real time or else we will just be ...

      By Shailesh Deshmukh
    • Wow the Govt has heard us

      All foreign vaccines can now come Into India. See attached. Didnt think it would happen so easily. Great work circle members. Your survey below contributed to this magic I am sure sure.. ...

      By Sarita Ravichandran
    • Travel plans of citizens and Covid 2nd wave

      Many families after no travel for over a year planned their summer travel as the COVID cases had reduced by February this year. However with the 10X rise in COVID cases from March 15th and a massiv...

      By LocalCircles Manager
    • 169,243 cases and Messed up Priorities

      India reported 169,243 new coronavirus cases, the biggest daily figure since the pandemic began. Models are now projecting an unreal 5 lakhs cases, 25000 hospitalizations and 3000 deaths...

      By Anita Chaturvedi
    • COVID 2nd wave - Mask and Social Distancing compliance must improve

      This survey is exactly right. Not just vaccination centers are super spreaders. Testing centers are even more. See whats happening in Ratlam Madhya Pradesh as they come out and share covid reports ...

      By Ajay Mittal
    • 18% experienced vaccine shortages, did you?

      As always, members of various circles were one of the first ones to report vaccine shortage issues in certain centers esp in Maharashtra and Delhi NCR region. Below is the link to our circle survey...

      By LocalCircles Manager
    • Jumping the Vaccine Queue: Finding Violators

      Govt of India after LocalCircles survey admitted that 24% of the vaccines went to people who were classified as health or front line worker due to setting/Jugaad/corruption in March. Now...

      By Sarika Bansal
Enter your email & mobile number and we will send you the instructions

Note - The email can sometime gets delivered to the spam folder, so the instruction will be send to your mobile as well

Please select a Circle that you want people to invite to.
Invite to
(Maximum 500 email ids allowed.)